| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Cabozantinib Malate |
| Appearance | White Powder |
| CAS NO. | 1140909-48-3 |
| MF | C32H31N7O6 |
| Storage | Keep in a cool, dry, dark location |
Cabozantinib Malate is an orally active tyrosine kinase inhibitor (TKI) that targets multiple receptor tyrosine kinases (RTKs) involved in tumor angiogenesis, growth, and metastasis. It is primarily used in the treatment of various types of cancer.
Cancer Treatment: Cabozantinib Malate is approved for the treatment of advanced renal cell carcinoma (RCC) and advanced hepatocellular carcinoma (HCC). It is also being investigated for use in other solid tumors.
Combination Therapy: It can be used in combination with other therapeutic agents to enhance the efficacy of cancer treatment. The combination therapy may involve targeting different pathways or mechanisms of action to achieve a synergistic effect.
Research and Development: Cabozantinib Malate serves as a tool compound in research for understanding the roles of RTKs in cancer development and progression. It also aids in the development of new therapeutic strategies targeting these kinases.
Angiogenesis Inhibition: By inhibiting the receptor, Cabozantinib Malate disrupts the formation of new blood vessels that nourish tumors, thereby starving them of oxygen and nutrients.
Tumor Growth Suppression: It inhibits the growth and proliferation of cancer cells by targeting other RTKs such as MET and AXL, which are involved in tumor cell survival, migration, and invasion.
Metastasis Reduction: By blocking the signaling pathways that promote cancer cell migration and invasion, Cabozantinib Malate helps to reduce the spread of tumors to other parts of the body.
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