Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Pomalidomide |
Appearance | Yellow Powder |
CAS NO. | 19171-19-8 |
MF | C13H16N2O4 |
Storage | Keep in a cool, dry, dark location |
Pomalidomide is a chemical compound belonging to the class of immunomodulatory drugs (IMiDs). It is an analog of thalidomide with modifications that enhance its potency and selectivity. The molecular formula of pomalidomide is C13H16N2O4 (not bolded as per the instruction).
Cancer Treatment: Pomalidomide is primarily used in the treatment of certain types of blood cancers, including multiple myeloma and myelodysplastic syndromes. It works by inhibiting the growth and proliferation of cancer cells.
Combination Therapy: It is often administered in combination with other medications, such as a monoclonal antibody, to enhance its therapeutic effects and improve patient outcomes.
Maintenance Therapy: Pomalidomide can also be used as a maintenance therapy to prolong the duration of remission and reduce the risk of relapse in patients with multiple myeloma.
Immunomodulation: Pomalidomide modulates the immune system by inhibiting the production of certain cytokines and promoting the differentiation and proliferation of immune cells, such as T-cells and natural killer cells, which are essential for fighting cancer.
Anti-angiogenic Effects: It exhibits anti-angiogenic properties by inhibiting the formation of new blood vessels that supply oxygen and nutrients to cancer cells, thereby starving them and preventing their growth.
Apoptosis Induction: Pomalidomide also induces apoptosis (programmed cell death) in cancer cells by activating specific signaling pathways and inhibiting the survival mechanisms of these cells.