Daptomycin Powder CAS 103060-53-3 Daptomycin Antibiotic Daptomycin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Sample: Available
• OEM: Available
• MOQ: 1kg
• CAS: 103060-53-3
• Keyword: Daptomycin
• Keyword 1: Daptomycin Powder
• Transport Package: 1kg Foil Bag /25kg Drum
• Specification: 99%
• Trademark: /
• Origin: China
• Production Capacity: 20000

Product Description

Product Description

Description

Daptomycin is the first entry of a new class of cyclic lipopeptide antibiotics that disrupts multiple aspects of bacterial membrane function including disruption of membrane potential and amino acid transport, inhibition of lipoteichoic acid synthesis and inhibition of peptidoglycan synthesis. It is indicated for the treatment of complicated skin and skinstructure infections (cSSSI) caused by a range of Gram-positive bacteria. This is distinct from previous classes of antibiotics that inhibit bacterial cell wall biosynthesis, bacterial DNA replication, and folate coenzyme biosynthesis. Due to this unique mechanism, cross-resistance has not been noted with any other class of antibiotics.

Product name	Daptomycin
Appearance	white Powder
Specification	99%
Shelf life	2 years when properly stored

Function and Application

Daptomycin is from Streptomyces (S.reseosporus) extracted from cyclic lipopeptide antibiotics a new structure of the fermentation broth, it not only has a novel chemical structure, and the mode of action and any one of the approved antibiotics are different: it is through the transport of amino acids disrupt the cell membrane, thus impeding the biosynthesis of bacterial cell wall peptidoglycan, change the nature of cell membrane, can damage the function of bacterial cell membrane in many aspects, and quickly kill gram positive bacteria.

In addition to the role of daptomycin in most clinically relevant gram positive bacteria, it is more important to have in vitro showed methicillin resistant (methicillin) strains, vancomycin and linezolid resistant properties with potent activity for this feature has very important clinical significance in patients with severe infection.