Factory 99% Etravirine Powder CAS 269055-15-4 Chemical Intermediate Etravirine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A866
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Etravirine
• CAS: 269055-15-4
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Etravirine
Appearance	White Powder
CAS NO.	269055-15-4
Storage	Keep in a cool, dry, dark location

 

Etravirine, also known as TMC125, is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). It belongs to a class of antiviral drugs specifically designed to target and inhibit the reverse transcriptase enzyme of HIV-1, thereby preventing the virus from replicating.

 

1. HIV-1 Treatment: Etravirine is primarily used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults who have already received antiretroviral therapy and have developed resistance to other NNRTIs.
2. Combination Therapy: As part of highly active antiretroviral therapy (HAART), etravirine helps to suppress HIV-1 viral load and restore or maintain immune function.
3. Experienced Patients: It is particularly useful in patients who have a history of treatment with other NNRTIs and have shown resistance to those drugs.

1. Inhibition of Reverse Transcriptase: Etravirine binds directly to the reverse transcriptase enzyme of HIV-1, disrupting its function and preventing the virus from transcribing its RNA into DNA, which is a crucial step in viral replication.
2. Antiviral Activity: By inhibiting reverse transcriptase, etravirine reduces the amount of virus in the body, slowing down the progression of HIV-1 infection and potentially lowering the risk of developing AIDS-related complications.
3. High Genetic Barrier to Resistance: Etravirine has a high genetic barrier to the development of resistance, meaning that it is less likely to lose its effectiveness over time due to mutations in the HIV-1 virus.