Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
Still deciding? Get samples of US$ 280/kg
Request Sample
|
Suppliers with verified business licenses
Audited by an independent third-party inspection agency
Product Name | Riluzole |
Appearance | White Powder |
CAS NO. | 1744-22-5 |
MF | C12H10N2O2 |
Storage | Keep in a cool, dry, dark location |
Riluzole is a pivotal drug in the treatment of ALS, with its mechanisms of action centered on glutamatergic inhibition and neuroprotection. Its applications and ongoing research highlight its potential in advancing the management of various neurological conditions.
Amyotrophic Lateral Sclerosis (ALS) Treatment: Riluzole is primarily prescribed for the treatment of ALS, a progressive neurodegenerative disease. It has been shown to extend survival and slow the progression of functional impairment in some patients.
Neuroprotective Effects: Due to its neuroprotective properties, riluzole is also being studied for potential applications in other neurological conditions, such as stroke and traumatic brain injury, although these uses are still under investigation.
Research Tool: In scientific research, riluzole serves as a valuable tool to investigate the mechanisms of glutamate-mediated neurotoxicity and neuroprotection, aiding in the development of new therapeutic strategies for neurological disorders.
Glutamate Inhibition: Riluzole functions by inhibiting the release of glutamate, an excitatory neurotransmitter, from presynaptic terminals. This reduction in glutamate levels helps to decrease neuronal excitability and prevent excitotoxicity, which is a key process in the progression of ALS.
Neuroprotective Mechanisms: By modulating glutamatergic neurotransmission, riluzole promotes neuroprotective mechanisms that may involve reducing oxidative stress, inflammation, and cell death.
Improving Patient Quality of Life: Through its disease-modifying effects, riluzole can help slow the decline in physical function and extend the duration of independent living for ALS patients, thereby improving their overall quality of life.