| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Guanidine HCl |
| Appearance | White Powder |
| CAS NO. | 50-01-1 |
| MF | C27H36N2O4 |
| Storage | Keep in a cool, dry, dark location |
Guanidine HCl, or guanidine hydrochloride, is a salt commonly used in biochemical research, pharmaceutical industry, and cell culture media. It is known for its ability to denature proteins, making it a valuable tool in the separation and purification of these macromolecules.
Biochemical Research: Guanidine HCl is widely used as a protein denaturant. By disrupting the internal hydrogen bonds and hydrophobic interactions within proteins, it aids in the separation and purification of these macromolecules, making it invaluable in biochemical studies.
Pharmaceutical Industry: As an intermediate in the synthesis of various drugs, Guanidine HCl is essential in the pharmaceutical industry. Its ability to alter protein conformations and its use in denaturing proteins make it a crucial component in drug discovery and development processes.
Cell Culture Media: Guanidine HCl is also used in cell culture media to help maintain optimal growth conditions. It can regulate the osmolarity and pH of the media, ensuring that cells grown in vitro have the best possible environment for proliferation.
Protein Denaturation: Guanidine HCl effectively denatures proteins by disrupting their native conformations, making them more susceptible to purification techniques such as chromatography and electrophoresis. This function is critical in biochemical studies where the isolation and analysis of proteins are necessary.
Membrane Permeabilization: Guanidine HCl has the ability to permeabilize cellular membranes, facilitating the release of intracellular components. This function is useful in cell lysis and extraction procedures, where the isolation of specific cellular components is required.
pH Regulation: In cell culture applications, Guanidine HCl helps maintain a stable pH environment. The regulation of pH is crucial for cell growth and proliferation, as cells are sensitive to changes in their external environment.
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