Chemical Intermediate Methotrexate Powder CAS 59-05-2 Antineoplastic Methotrexate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Methotrexate
• CAS: 59-05-2
• Mf: C20h16n8o5
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

 

Methotrexate is an antimetabolite and folate antagonist, which means it disrupts the metabolism and utilization of folate, an essential vitamin for cell growth and division.

 

Product Name	Methotrexate
Appearance	Yellow Powder
CAS NO.	59-05-2
Molecular Formula	C20H16N8O5
Storage	Keep in a cool, dry, dark location

 

1. Oncology: It is commonly used in the treatment of various types of cancer, particularly acute lymphocytic leukemia, lymphomas, and some solid tumors.
2. Rheumatology: Methotrexate is a cornerstone drug in the management of rheumatoid arthritis, helping to reduce inflammation and joint damage.
3. Dermatology: It is also prescribed for certain skin conditions such as psoriasis, where it can help control the rapid growth of skin cells.

1. Inhibition of DNA Synthesis: By blocking the action of dihydrofolate reductase, methotrexate inhibits the synthesis of purine nucleotides and thymidylate, essential for DNA replication.
2. Anti-inflammatory Effects: In autoimmune diseases like rheumatoid arthritis, it exhibits immunomodulatory properties, reducing the immune system's attack on healthy tissues.
3. Cytoreductive Action: In cancer treatment, it helps to shrink tumor size by inhibiting the rapid division of cancer cells.

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