Chemical Intermediate Gemcitabine HCl CAS 122111-03-9 Anti-Cancer Gemcitabine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Gemcitabine
• CAS: 122111-03-9
• Mf: C9h11f2n3o4.Clh
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

 

Gemcitabine HCl is a nucleoside analog that functions as an anticancer agent by inhibiting DNA synthesis in cancer cells.

 

 

Product Name	Gemcitabine HCl
Appearance	White Powder
CAS NO.	122111-03-9
Molecular Formula	C9H11F2N3O4P·HCl
Storage	Keep in a cool, dry, dark location

 

1. DNA Synthesis Inhibition: Gemcitabine HCl is metabolized into its active form within cells, which then inhibits DNA synthesis by competitively inhibiting deoxycytidine kinase, a key enzyme in DNA replication.

2. Cell Cycle Arrest and Apoptosis: By disrupting DNA synthesis, Gemcitabine HCl causes cancer cells to arrest in the S-phase of the cell cycle, leading to cell death through apoptosis.

3. Antitumor Activity: Gemcitabine HCl exhibits broad-spectrum antitumor activity against various cancer types, making it a valuable addition to the armamentarium of cancer treatments.

 

1. Cancer Treatment: Gemcitabine HCl is primarily used in the treatment of solid tumors, including pancreatic cancer, non-small cell lung cancer, and breast cancer.

2. Combination Therapy: It is often administered in combination with other chemotherapy drugs to enhance treatment efficacy and reduce the risk of recurrence.

3. Intravenous Administration: Gemcitabine HCl is typically administered through intravenous infusion over a specified period, usually once a week.

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