Factory 99% Acriflavine HCl Powder CAS 8063-24-9 Chemical Intermediate Acriflavine HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A817
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Acriflavine HCl
• CAS: 8063-24-9
• Appearance: Red Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Acriflavine HCl
Appearance	Red Powder
CAS NO.	8063-24-9
Storage	Keep in a cool, dry, dark location

 

Acriflavine HCl is defined as a chemical compound that serves as a HIF-1α (hypoxia-inducible factor 1-alpha) inhibitor.

 

1. Biological Research: Acriflavine HCl is commonly used in biological research settings to study the role of HIF-1α in various cellular processes. Its ability to target HIF-1α-mediated pathways makes it a valuable tool for investigating hypoxia-related responses in cells.
2. Pharmaceutical Industry: Due to its HIF-1α inhibitory activity, Acriflavine HCl has potential applications in the pharmaceutical industry. It may be considered for the development of new therapeutic agents targeting HIF-1α-related diseases or conditions.
3. Veterinary Medicine: Acriflavine HCl has also been used as a disinfectant and antiprotozoal agent in veterinary medicine, particularly for treating certain parasitic infections in animals.

1. HIF-1α Inhibition: The primary function of Acriflavine HCl is to inhibit the activity of HIF-1α, a transcription factor that plays a crucial role in the cellular response to hypoxia. By inhibiting HIF-1α, Acriflavine HCl can affect the expression of genes involved in angiogenesis, glycolysis, and other hypoxic responses.
2. Reduction of PGK1: In vitro and in vivo studies have shown that Acriflavine HCl can decrease the levels of PGK1 (phosphoglycerate kinase 1) , two proteins that are upregulated by HIF-1α and play important roles in cancer progression and angiogenesis.
3. Antiprotozoal Activity: In addition to its HIF-1α inhibitory activity, Acriflavine HCl has been shown to exhibit antiprotozoal activity against certain parasites, such as those causing babesiosis in animals. This makes it a potential candidate for the treatment of such infections in veterinary medicine.