Factory 99% Mitiglinide Calcium Powder CAS 207844-01-7 Chemical Intermediate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A993
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Mitiglinide Calcium
• CAS: 207844-01-7
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Mitiglinide Calcium
Appearance	White Powder
CAS NO.	207844-01-7
Storage	Keep in a cool, dry, dark location

 

Mitiglinide calcium is a rapid-acting, short-duration oral hypoglycemic agent classified as a potassium channel blocker. It selectively inhibits ATP-sensitive potassium (KATP) channels on pancreatic β-cells, triggering calcium influx and secretion in a glucose-dependent manner. This mechanism reduces postprandial hyperglycemia without causing sustained release, minimizing the risk of hypoglycemia.

 

1. Type 2 Diabetes Management: Used as monotherapy or adjunct to diet/exercise in patients with inadequate glycemic control, particularly those with pronounced postprandial glucose spikes.
2. Combination Therapy: Administered alongside metformin, DPP-4 inhibitors, or α-glucosidase inhibitors to enhance overall glycemic control.
3. Special Populations: Suitable for elderly patients or those with erratic meal schedules due to its flexible dosing (pre-meal administration) and short duration of action.

1. Secretion Stimulation: Closes KATP channels in β-cells, depolarizing the membrane and promoting exocytosis via voltage-gated calcium channels.
2. Glucose-Dependent Action: Enhances release only in the presence of elevated blood glucose, reducing off-target effects and hypoglycemia risk.
3. β-Cell Preservation: By mimicking physiological secretion patterns, it may mitigate β-cell exhaustion associated with chronic hyperglycemia.