Carbamazepine Powder CAS 298-46-4 Anticonvulsant Carbamazepine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Sample: Available
• OEM: Available
• MOQ: 1kg
• CAS: 298-46-4
• Keyword: Carbamazepine
• Keyword 1: Carbamazepine Powder
• Transport Package: 1kg Foil Bag /25kg Drum
• Specification: 99%
• Trademark: /
• Origin: China
• Production Capacity: 20000

Product Description

Description

Carbamazepine is white or white-like crystalline powder, which belongs to benzodiazepine antiepileptic drug and has antiepileptic effect similar to phenytoin sodium. It is most effective for psychomotor seizures, and also effective for large seizures, localized seizures and mixed seizures. Carbamazepine has better anti-peripheral neuralgia effect than phenytoin sodium, and can be used for trigeminal neuralgia and glossopharyngeal neuralgia. It can also be used for treating arrhythmia and diabetes insipidus.

Product name	Carbamazepine
Appearance	White Powder
Specification	99%
Shelf life	2 years when properly stored

Function

Carbamazepine (CBZ) is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia. It is also used off-label for a variety of indications, including attention-deficit hyperactivity disorder (ADHD), schizophrenia, phantom limb syndrome, complex regional pain syndrome, paroxysmal extreme pain disorder, neuromyotonia, intermittent explosive disorder, borderline personality disorder and post-traumatic stress disorder. It has been seen as safe for pregnant women to use carbamazepine as a mood stabilizer, but, like other anticonvulsants, intrauterine exposure is associated with spina bifida and neurodevelopmental problems.

Application
Membrane stabilization can reduce the permeability of nerve cell membrane to Na+ and Ca2+, thus reducing the excitability of cells and prolonging the refractory period; It may also enhance the synaptic transmission function of GABA. The anticonvulsant mechanism is similar to phenytoin, which inhibits the late ankylosis of synaptic site and limits the spread of abnormal discharges in epileptogenic focus. It can also inhibit the electrical activity in the anterior ventral nucleus of thalamus. The mechanism of analgesia is unknown, which may reduce synaptic transmission in central nervous system.