| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Cefazolin Sodium |
| Appearance | White Powder |
| CAS NO. | 27164-46-1 |
| MF | C16H17N3O4SNa |
| Storage | Keep in a cool, dry, dark location |
Cefazolin Sodium is a versatile antibiotic with a well-established role in clinical practice, providing a reliable option for the management of various bacterial infections.
Antibacterial Therapy: Cefazolin Sodium is primarily used in the treatment of bacterial infections caused by susceptible organisms. It is administered parenterally, making it suitable for cases where oral therapy is not feasible or when rapid onset of antibacterial action is required.
Surgical Prophylaxis: Prior to surgical procedures, Cefazolin Sodium can be used to prevent postoperative infections. Its broad-spectrum activity against common surgical pathogens makes it a valuable prophylactic agent.
Pediatric and Geriatric Use: Appropriate dosages are recommended for use in pediatric and geriatric patients, adjusting for age, weight, and renal function to ensure safe and effective therapy.
Bacterial Cell Wall Synthesis Inhibition: Cefazolin Sodium functions by inhibiting the synthesis of the bacterial cell wall, a critical component for bacterial survival. This leads to the lysis (bursting) of the bacterial cell and subsequent elimination of the pathogen.
Broad-Spectrum Activity: It exhibits activity against a wide range of Gram-positive and some Gram-negative bacteria, including Staphylococcus aureus (including methicillin-susceptible strains), Streptococcus pneumoniae, Escherichia coli, and Klebsiella pneumoniae, among others.
Beta-Lactamase Stability: Unlike some other cephalosporins, Cefazolin Sodium is relatively stable to beta-lactamases, enzymes produced by certain bacteria to inactivate beta-lactam antibiotics. This stability contributes to its effectiveness against a broader spectrum of bacteria.
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