Chemical Intermediate 7, 8-Dihydroxyflavone Powder 7, 8-Dhf CAS 38183-03-8

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: 7, 8-Dhf
• CAS: 38183-03-8
• Mf: C15h10o4
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

 

7,8-Dihydroxyflavone (7,8-DHF) is a potent and selective TrkB receptor agonist (Kd≈320 nM). TrkB receptor is the main signal receptor of brain-derived neurotrophic factor. 7,8-Dihydroxyflavone (7,8-DHF) is a potential nootropic that may improve overall brain health, mood, and cognitive function. It may also be of benefit for several neurodegenerative and neurodevelopmental disorders, as well as obesity and elevated blood pressure..  .

 

 

Product Name	7, 8-Dihydroxyflavone Powder CAS 38183-03-8 7, 8-Dhf
Appearance	Yellow powder
Molecular formula	C15h10o4
Molecular Weight	254.24
Keywords	7 8-Dihydroxyflavone;7 8-Dhf Powder;7, 8-Dihydroxyflavone Powder
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

 

1. Improve Memory and Learning
2. Promote Brain Repair
   7,8-DHF promoted the repair of damaged neurons .
3. Be Neuroprotective
4. Has Antioxidant Effects
5. Has Anti-Inflammatory Effects
   7,8-DHF decreases the release of inflammatory factors in brain cells by blocking NF-κB .
6. 7,8-DHF has a strong therapeutic effect on Alzheimer's disease, and can inhibit obesity by activating muscle TrkB..

1. 7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally bioavailable and able to penetrate the blood-brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease

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