Factory 99% Use for Indigestion CAS 156925-25-6 Mosapride Citrate Dihydrate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A318
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Mosapride Citrate Dihydrate
• CAS: 156925-25-6
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Use for Indigestion
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Mosapride Citrate Dihydrate
Appearance	White Powder
CAS NO.	156925-25-6
Molecular Formula	C27H33ClFN3O10
Storage	Keep in a cool, dry, dark location

 

Mosapride Citrate Dihydrate is a chemical compound, specifically a gastroprokinetic agent, with the formula C27H33ClFN3O10. It is a citrate salt of mosapride in its dihydrated form, commonly used in pharmaceutical preparations for the treatment of gastrointestinal disorders.

 

 

1. Treatment of Gastrointestinal Disorders: Mosapride Citrate Dihydrate is primarily applied in the treatment of functional dyspepsia, chronic gastritis, and gastroesophageal reflux disease (GERD), where it enhances gastrointestinal motility.
2. Improvement of Digestive Symptoms: It is also used to alleviate symptoms such as nausea, vomiting, early satiety, and bloating, which are often associated with gastrointestinal motility disorders.
3. Adjuvant Therapy: In some cases, Mosapride Citrate Dihydrate may be used as an adjuvant therapy in combination with other medications to enhance the overall therapeutic effect in the management of gastrointestinal conditions.

1. 5-HT4 Receptor Agonist Activity: Mosapride Citrate Dihydrate functions as a selective 5-hydroxytryptamine 4 (5-HT4) receptor agonist, which stimulates the release of acetylcholine in the gastrointestinal tract, thereby promoting smooth muscle contraction and increasing gastrointestinal motility.
2. Concentration-Dependent Inhibition of Kv4.3: It has been shown to inhibit Kv4.3 potassium channels in a concentration-dependent manner, with an IC50 value of 15.2 μM.
3. Stimulation of Upper Gastrointestinal Motility: In vivo studies have demonstrated that Mosapride Citrate Dihydrate selectively stimulates upper gastrointestinal motility, as evidenced by increased antral motor activity in animal models.