Factory 99% Dantrolene Sodium Powder CAS 24868-20-0 Chemical Intermediate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A944
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Dantrolene Sodium
• CAS: 24868-20-0
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Dantrolene Sodium
Appearance	White Powder
CAS NO.	24868-20-0
Storage	Keep in a cool, dry, dark location

 

Dantrolene Sodium, with the CAS number 14663-23-1 and a molecular weight of 336.235, is a skeletal muscle relaxant that acts by interfering with the excitation-contraction coupling in muscle fibers. It is also known as a ryanodine receptor antagonist and a sarcoplasmic reticulum calcium release inhibitor.

 

1. Medical Treatment: Dantrolene Sodium is primarily used in the treatment of spasticity and other neuromuscular disorders. It helps to relax the skeletal muscles and reduce muscle tone.
2. Anesthetic Adjuvant: In anesthesia, it can be used as an adjuvant to prevent or manage malignant hyperthermia, a potentially life-threatening condition characterized by a rapid increase in body temperature and muscle rigidity.
3. Experimental Research: It is also used in experimental research to study muscle contraction and relaxation mechanisms, as well as in the development of new muscle relaxants.

1. Sarcoplasmic Reticulum Calcium Release Inhibition: Dantrolene Sodium inhibits the release of calcium ions from the sarcoplasmic reticulum, which is essential for muscle contraction. By blocking this process, it reduces muscle contractility.
2. Ryanodine Receptor Antagonism: It acts as an antagonist at the ryanodine receptor, a calcium channel in the sarcoplasmic reticulum. This antagonism prevents the excessive release of calcium and thus muscle contraction.
3. Neuromuscular Relaxation: Overall, Dantrolene Sodium functions to relax skeletal muscles by interfering with the calcium signaling pathways that mediate muscle contraction.