Chemical Intermediate Efavirenz CAS 154598-52-4 Efavirenz Powder

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Efavirenz
• CAS: 154598-52-4
• Mf: C14h9clf3no2
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

What is Efavirenz ?

Efavirenz D5 (Sustiva)84 is also mandated for use with at leasttwo other antiretroviral agents. The compound is morethan 99% protein bound, and CSF concentrations exceedthe free fraction in the serum. Metabolism occurs in theliver. The half-life of a single dose of Efavirenz D5 is 52 to 76hours, and 40 to 55 after multiple doses (the drug inducesits own metabolism). Peak concentration is achieved in 3to 8 hours. Elimination is 14% to 34% in urine (as metabolites)and 16% to 41% in feces (primarily as Efavirenz D5).The oral dosage form is supplied as a capsule.

 

 

Product Name	High Quality API Antiretroviral Medicine Raw Material Efavirenz Powder CAS 154598-52-4 Efavirenz
Appearance	powder
cas	154598-52-4
Assay	90%
Keywords	Efavirenz;Efavirenz Powder;Powder Raw Material Efavirenz
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

1. Efavirenz is one of the most commonly prescribed antiretroviral medications in the world. Several large randomized, controlled trials[RCTs] have demonstrated the superior ability of efavirenz to suppress the HIV virus when used as part of a 3-drug cocktail[2]. The introduction of Atripla in 2006 combined efavirenz and two other agents into a single pill, once-daily formulation. This formulation was more convenient and better tolerated than alternatives, and thus resulted in improved adherence to antiretroviral medications[3]. However, neuropsychiatric side effects associated with efavirenz have been reported to occur in 40-50% of patients and represent one of the limiting factors of this regime

1. For use in combination treatment of HIV infection (AIDS)

 

Pro-xylane	Potassium azeloyl diglycinate
Ghk-Cu or other Cosmetic peptides	Glutathione
Spermidine	5-deazaflavin
PQQ	Coenzyme Q10
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