Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Ribociclib |
Appearance | White Powder |
CAS NO. | 1211441-98-3 |
MF | C23H30N8O |
Storage | Keep in a cool, dry, dark location |
Ribociclib, also known as LEE-011, is a potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). Developed by Novartis Pharmaceuticals Ltd., this drug targets the cyclin D1/CDK4 and cyclin D3/CDK6 cellular pathways, exhibiting significant antitumor activity. Ribociclib binds to cyclin proteins, facilitating the transition of cell cycle phases, initiating DNA synthesis, and regulating cellular transcription. Approved by the FDA in March 17, 2017, it is marketed under the brand name Kisqali.