Factory 99% Nicergoline Powder CAS 27848-84-6 Chemical Intermediate Nicergoline

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A862
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Nicergoline
• CAS: 27848-84-6
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Nicergoline
Appearance	White Powder
CAS NO.	27848-84-6
Storage	Keep in a cool, dry, dark location

 

Nicergoline is a semi-synthetic ergot alkaloid derivative, characterized by its chemical formula C24H26BrN3O3 and a molecular weight of 484.39. It has the CAS number 27848-84-6.

 

1. Cerebrovascular Diseases: Nicergoline is widely used in the treatment of acute or chronic cerebrovascular disorders, including improvement of post-stroke depression, vascular cognitive impairment, and dementia.
2. Neurological Function Enhancement: It is employed to enhance neurological function recovery after cerebral infarction and neurosurgical procedures.
3. Peripheral Circulation Disorders: Nicergoline is also indicated for the management of peripheral circulation disorders, such as limb vascular occlusion and other symptoms of impaired peripheral circulation like Raynaud's syndrome.

1. Vasodilatory Effect: Nicergoline acts as an α1A-adrenergic receptor antagonist, causing vasodilation and thereby improving cerebral blood flow.
2. Metabolic Enhancement: It enhances brain metabolism by increasing the utilization of oxygen and glucose, as well as promoting the biosynthesis of brain proteins.
3. Neuroprotective Properties: Nicergoline exhibits neuroprotective effects by promoting the release of neurotransmitters, particularly dopamine, and inhibiting apoptosis, inflammation, and oxidative stress in the brain. It has been shown to improve cognitive function in animal models of Alzheimer's disease.