Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
Still deciding? Get samples of US$ 320/kg
Request Sample
|
Suppliers with verified business licenses
Audited by an independent third-party inspection agency
Product Name | Aztreonam |
Appearance | White Powder |
CAS NO. | 78110-38-0 |
Storage | Keep in a cool, dry, dark location |
Aztreonam is a monocyclic beta-lactam antibiotic, specifically classified as a monobactam. It possesses a unique chemical structure that distinguishes it from other beta-lactam antibiotics and exhibits potent antibacterial activity against a variety of Gram-negative bacteria.
Treatment of Gram-negative Infections: Aztreonam is primarily applied in the treatment of infections caused by sensitive aerobic Gram-negative bacteria. This includes respiratory infections, urinary tract infections, intra-abdominal infections, and sepsis.
Alternative to Penicillin and Cephalosporins: Due to its unique antibacterial spectrum and mechanism of action, Aztreonam can be used as an alternative to penicillin and cephalosporins in patients who are allergic to these drugs.
Combination Therapy: Aztreonam is also used in combination with other antibiotics to broaden the antibacterial spectrum and enhance therapeutic efficacy.
Inhibition of Bacterial Cell Wall Synthesis: The primary function of Aztreonam is to inhibit the synthesis of bacterial cell walls, leading to the death of the bacteria. This antibacterial activity is specific to Gram-negative bacteria.
Broad-spectrum Antibacterial Activity: Aztreonam exhibits broad-spectrum antibacterial activity against many species of Enterobacteriaceae, Pseudomonas aeruginosa, and other Gram-negative bacteria.
Low Toxicity and Good Tolerance: Aztreonam is generally well-tolerated by patients, with low toxicity and a relatively low incidence of adverse reactions. However, it should be used with caution in patients with renal impairment due to potential accumulation and increased risk of adverse effects.